Comments on: Characteristics and Clinical Significance of Late Gadolinium Enhancement by Contrast-Enhanced Magnetic Resonance Imaging in Patients With Hypertrophic Cardiomyopathy

By: Paul Schoenhagen, MD

Paul Schoenhagen, MD — Wed, 10 Feb 2010 20:44:49 +0000

Also check:

Cardiac magnetic resonance detection of myocardial scarring in hypertrophic cardiomyopathy: correlation with histopathology and prevalence of ventricular tachycardia.
Kwon DH, Smedira NG, Rodriguez ER, Tan C, Setser R, Thamilarasan M, Lytle BW, Lever HM, Desai MY.
J Am Coll Cardiol. 2009 Jul 14;54(3):242-9.
PMID: 19589437

By: Phillip M. Young, MD

Phillip M. Young, MD — Wed, 10 Feb 2010 16:12:45 +0000

It would be interesting whether a quantitative estimate of the degree of enhancement is prognostic as well.

LV remodeling has also been associated with delayed enhancement in hypertrophic cardiomyopathy. See the related article below:

Gender-specific differences in left ventricular remodelling and fibrosis in hypertrophic cardiomyopathy: insights from cardiovascular magnetic resonance.
Schulz-Menger J, Abdel-Aty H, Rudolph A, Elgeti T, Messroghli D, Utz W, Boyé P, Bohl S, Busjahn A, Hamm B, Dietz R.
Eur J Heart Fail. 2008 Sep;10(9):850-4.
PMID: 18692438

By: Jacobo Kirsch, MD

Jacobo Kirsch, MD — Tue, 09 Feb 2010 17:43:09 +0000

Solid data that supports the use of LGE in HOCM patients for risk-stratification.

The study demonstrates a direct association between the presence of LGE and SCD or appropriate ICD discharges.