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	<title>Comments on: The Dynamic Nature of Coronary Artery Lesion Morphology Assessed By Serial Virtual Histology Intravascular Ultrasound Tissue Characterization</title>
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	<link>http://www.thepreparedminds.com/archives/1624</link>
	<description>In the field of observation, chance favors the prepared minds.</description>
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		<title>By: Jacobo Kirsch, MD</title>
		<link>http://www.thepreparedminds.com/archives/1624/comment-page-1#comment-1756</link>
		<dc:creator>Jacobo Kirsch, MD</dc:creator>
		<pubDate>Fri, 30 Apr 2010 17:32:45 +0000</pubDate>
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		<description>Very interesting data!

One question that I had while reading it, was if there were any differences in plaque evolution between groups of patients with specific characteristics, such as diabetes, tobacco abuse, or the use of certain medications (53 of the 99  were on statins!).</description>
		<content:encoded><![CDATA[<p>Very interesting data!</p>
<p>One question that I had while reading it, was if there were any differences in plaque evolution between groups of patients with specific characteristics, such as diabetes, tobacco abuse, or the use of certain medications (53 of the 99  were on statins!).</p>
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		<title>By: Paul Schoenhagen, MD</title>
		<link>http://www.thepreparedminds.com/archives/1624/comment-page-1#comment-1702</link>
		<dc:creator>Paul Schoenhagen, MD</dc:creator>
		<pubDate>Mon, 26 Apr 2010 02:27:22 +0000</pubDate>
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		<description>Interesting data, showing the temporary nature of &#039;vulnerable&#039; plaques!

See the recent post of April 20th:

Composition of Carotid Atherosclerotic Plaque Is Associated With Cardiovascular Outcome: A Prognostic Study.
Circulation. 2010; 121(4):1941-1950.
Willem E. Hellings, Wouter Peeters, Frans L. Moll, Sebastiaan R.D. Piers, Jessica van Setten, Peter J. Van der Spek, Jean-Paul P.M., et al.
PMID: &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/20404256&quot; rel=&quot;nofollow&quot;&gt;20404256&lt;/a&gt;

See also the following manuscript, which discusses possible misclassification with IVUS and OCT:

Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro.
T. P. M. Goderie, G. van Soest, H. M. Garcia-Garcia, N. Gonzalo, S. Koljenović, G. J. L. H. van Leenders, F. Mastik, E. Regar, J. W. Oosterhuis, et al.
Int J Cardiovasc Imaging. 2010 Apr 16
PMID: &lt;a href=&quot;http://www.ncbi.nlm.nih.gov/pubmed/20396951&quot; rel=&quot;nofollow&quot;&gt;20396951&lt;/a&gt;</description>
		<content:encoded><![CDATA[<p>Interesting data, showing the temporary nature of &#8216;vulnerable&#8217; plaques!</p>
<p>See the recent post of April 20th:</p>
<p>Composition of Carotid Atherosclerotic Plaque Is Associated With Cardiovascular Outcome: A Prognostic Study.<br />
Circulation. 2010; 121(4):1941-1950.<br />
Willem E. Hellings, Wouter Peeters, Frans L. Moll, Sebastiaan R.D. Piers, Jessica van Setten, Peter J. Van der Spek, Jean-Paul P.M., et al.<br />
PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20404256" rel="nofollow">20404256</a></p>
<p>See also the following manuscript, which discusses possible misclassification with IVUS and OCT:</p>
<p>Combined optical coherence tomography and intravascular ultrasound radio frequency data analysis for plaque characterization. Classification accuracy of human coronary plaques in vitro.<br />
T. P. M. Goderie, G. van Soest, H. M. Garcia-Garcia, N. Gonzalo, S. Koljenović, G. J. L. H. van Leenders, F. Mastik, E. Regar, J. W. Oosterhuis, et al.<br />
Int J Cardiovasc Imaging. 2010 Apr 16<br />
PMID: <a href="http://www.ncbi.nlm.nih.gov/pubmed/20396951" rel="nofollow">20396951</a></p>
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