Cardiovascular magnetic resonance has revolutionised the diagnosis of cardiomyopathy, particularly through the use of late gadolinium enhancement imaging which provides the unique opportunity to assess myocardial fibrosis in vivo. More recently, the prognostic capability of cardiovascular magnetic resonance to predict outcomes has been assessed. Traditional risk markers do not at present adequately predict outcomes in either dilated cardiomyopathy or hypertrophic cardiomyopathy, which are the two most common causes of primary heart muscle disease. Many of these existing markers reflect underlying disease severity. Given the important role fibrosis is thought to play in the pathogenesis and sequelae of these cardiomyopathies, the presence and amount of fibrosis has been proposed as a potential novel risk factor for adverse events. This paper reviews the evidence for late gadolinium enhancement as a prognostic marker in dilated and hypertrophic cardiomyopathy and highlights the challenges ahead.
Cardiopulmonary Imaging, Section Head
Cleveland Clinic Florida
Latest posts by Jacobo Kirsch (see all)
- Evaluation of Diastolic Function by Three-Dimensional Volume Tracking of the Mitral Annulus With Cardiovascular Magnetic Resonance: Comparison with Tissue Doppler Imaging - September 21, 2014
- Assessment of Sub-Clinical Acute Cellular Rejection After Heart Transplantation: Comparison of Cardiac Magnetic Resonance Imaging and Endomyocardial Biopsy - September 15, 2014
- Value of CMR for the Differential Diagnosis of Cardiac Masses CME - September 9, 2014