OBJECTIVES: Using multislice computed tomography (MSCT), we sought to evaluate the geometry and apposition of the CoreValve ReValving System (CRS, Medtronic, Luxembourgh, Luxembourgh) in patients with aortic stenosis. Background: There are no data on the durability of percutaneous aortic valve replacement. Geometric factors may affect durability.
METHODS: Thirty patients had MSCT at a median 1.5 months (interquartile range [IQR] 0 to 7 months) after percutaneous aortic valve replacement. Axial dimensions and apposition of the CRS were evaluated at 4 levels: 1) the ventricular end; 2) the nadir; 3) central coaptation of the CRS leaflets; and 4) commissures. Orthogonal smallest and largest diameters and cross-sectional surface area were measured at each level.
RESULTS: The CRS (26-mm: n = 14, 29-mm: n = 16) was implanted at 8.5 mm (IQR 5.2 to 11.0 mm) below the noncoronary sinus. None of the CRS frames reached nominal dimensions. The difference between measured and nominal cross-sectional surface area at the ventricular end was 1.6 cm2 (IQR 0.9 to 2.6 cm2) and 0.5 cm2 (IQR 0.2 to 0.7 cm2) at central coaptation. At the level of central coaptation the CRS was undersized relative to the native annulus by 24% (IQR 15% to 29%). The difference between the orthogonal smallest and largest diameters (degree of deformation) at the ventricularend was 4.4 mm (IQR 3.3 to 6.4 mm) and it decreased progressively toward the outflow. Incomplete apposition of the CRS frame was present in 62% of patients at the ventricular end and was ubiquitous at the central coaptation and higher.
CONCLUSIONS: Dual-source MSCT demonstrated incomplete and nonuniform expansion of the CRS frame, but the functionally important mid-segment was well expanded and almost symmetrical. Undersizing and incomplete apposition were seen in the majority of patients.
Imaging Institute and
Latest posts by Schoenhagen Paul (see all)
- Outcomes in hypertrophic cardiomyopathy patients with and without atrial fibrillation: a survival meta-analysis. - February 21, 2017
- Stenotic Flow Reserve Derived from Quantitative Coronary Angiography has Modest but Incremental Value in Predicting Functionally Significant Coronary Stenosis as Evaluated by Fractional Flow Reserve - February 9, 2017
- Gadolinium Retention in the Body and Brain: Is It Time for an International Joint Research Effort? - January 13, 2017