Endovascular Abdominal Aortic Aneurysm Repair: Nonenhanced Volumetric CT for Follow-up

OBJECTIVES: To evaluate the clinical usefulness of volumetric analysis at nonenhanced computed tomography (CT) as the sole method with which to follow up endovascular abdominal aortic aneurysm repair (EVAR) and to identify endoleaks causing more than 2% volumetric increase from the previous volume determination.

METHODS: The study had institutional review board approval. Images were reviewed retrospectively in a HIPAA-compliant manner for 230 CT studies in 70 patients (11 women, 59 men; mean age, 74 years) who underwent EVAR. The scannning protocol consisted of three steps: (a) contrast material-enhanced CT angiography before endovascular stent placement, (b) contrast-enhanced CT angiography 0-3 months after repair to depict immediate complications, and (c) nonenhanced CT at 3, 6, and 12 months after repair. At each follow-up visit, immediate aortic volume analysis was performed. If the interval volumetric change was 2% or less, no further imaging was performed. If the volume increased by more than 2% on the nonenhanced CT image, contrast-enhanced CT angiography was performed immediately to identify the suspected endoleak. Confidence intervals (CIs) were obtained by using bootstrapping to account for repeated measurements in the same patients.

RESULTS: Mean volume decrease was -3.2% (95% CI: -4.7%, -1.9%) in intervals without occurrence of a clinically relevant endoleak (n = 183). Types I and III high-pressure endoleaks (n = 10) showed a 10.0% (95% CI: 5.0%, 18.2%) interval volumetric increase. Type II low-pressure endoleaks (n = 37) showed a 5.4% (95% CI: 4.6%, 6.2%) interval volumetric increase. Endoleaks associated with minimal aortic volume increase of less than 2% did not require any intervention. This protocol reduced radiation exposure by approximately 57%-82% in an average-sized patient.

CONCLUSIONS: Serial volumetric analysis of aortic aneurysm with nonenhanced CT serves as an adequate screening test for endoleak, causing volumetric increase of more than 2% from the volume seen at the previous examination. 

PMID: 19703867

Posted in Computed Tomography, Invasive Imaging and tagged , , .


  1. See also:
    Endoleaks after endovascular abdominal aortic aneurysm repair: detection with dual-energy dual-source CT.
    Stolzmann P, Frauenfelder T, Pfammatter T, Peter N, Scheffel H, Lachat M, Schmidt B, Marincek B, Alkadhi H, Schertler T.
    Radiology. 2008 Nov;249(2):682-91.

  2. See also:

    Incomplete Endograft Apposition to the Aortic Arch: Bird-Beak Configuration Increases Risk of Endoleak Formation after Thoracic Endovascular Aortic Repair.
    Takuya Ueda, Dominik Fleischmann, Michael D. Dake, Geoffrey D. Rubin, and Daniel Y. Sze.
    Radiology 2010;255 645-652.

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