Myocardial Tissue Tagging With Cardiovascular Magnetic Resonance

Cardiovascular magnetic resonance (CMR) is currently the gold standard for assessing both global and regional myocardial function. New tools for quantifying regional function have been recently developed to characterize early myocardial dysfunction in order to improve the identification and management of individuals at risk for heart failure. Of particular interest is CMR myocardial tagging, a non-invasive technique for assessing regional function that provides a detailed and comprehensive examination of intra-myocardial motion and deformation. Given the current advances in gradient technology, image reconstruction techniques, and data analysis algorithms, CMR myocardial tagging has become the reference modality for evaluating multidimensional strain evolution in the human heart. This review presents an in depth discussion on the current clinical applications of CMR myocardial tagging and the increasingly important role of this technique for assessing subclinical myocardial dysfunction in the setting of a wide variety of myocardial disease processes. Ahkello Witherspoon Jersey

PMID: 20025732

Posted in Magnetic Resonance Imaging and tagged , , , , .


  1. Tissue tagging is a MRI technique with similarity to Echo speckle tracking. In fact, speckle tracking has been validated against tagging, e.g.:

    Measurement of ventricular torsion by two-dimensional ultrasound speckle tracking imaging.
    Notomi Y, Lysyansky P, Setser RM, Shiota T, Popović ZB, Martin-Miklovic MG, Weaver JA, Oryszak SJ, Greenberg NL, White RD, Thomas JD.
    J Am Coll Cardiol. 2005 Jun 21;45(12):2034-41.

  2. Incredible review! Very thorough in both the physics and technique aspects of tagging as well as in its clinical significance.

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